Treatment with Vetoryl®

Your pet has had a diagnosis of hyperadrenocorticism, and your veterinarian has prescribed Vetoryl®. Although this medication does not cure the disease, it reduces the production of cortisol by the adrenal glands, thus eliminating unwanted clinical signs. This treatment requires careful monitoring, so please read the following carefully:

In general, Vetoryl® should be administered once a day, as prescribed by your veterinarian, with a meal. The capsules should not be opened, so it might be necessary for your veterinarian to prescribe a combination of capsules of varying dosages.

The first follow up will normally be scheduled 10 to 14 days after the beginning of treatment. An ACTH stimulation test should then be performed to evaluate the response to treatment, accompanied by blood tests chosen by your veterinarian (at least one measurement of electrolytes). Indeed, it is essential to detect any side effect or any change in the state of health of your animal that may affect the smooth course of treatment. It is important to do the ACTH stimulation test 4 to 6 hours after administration of Vetoryl®.

If the dosage is adequate, the next follow-up will normally be done after one month, and subsequent checks every 3 months. If the dosage changes, the next visit should be scheduled again after 10-14 days.

It should be noted that some patients will benefit from a medication administration twice a day rather than once a day. For example, if the symptoms are under control for only part of the day, you should consider this option with your veterinarian.

Side effects

The most common side effects are a loss of appetite, vomiting, lethargy, diarrhea and weakness. More rarely, more serious side effects can occur: severe depression, hemorrhagic diarrhea, collapse, and / or hypoadrenocorticism crisis (lack of cortisol).

This last condition, if left untreated, can have serious consequences, but it can be detected early by measuring electrolytes, so it is imperative to follow your veterinarian's recommendations for follow-up.

If you notice any side effects, please stop giving Vetoryl® immediately and contact your veterinarian, and do not hesitate to contact an emergency center if necessary.


The product cannot be used for dogs with renal or hepatic insufficiency or on breeding animals. In addition, it should be used with caution in animals suffering from anemia.

With regard to drug interactions, precautions should be taken before prescribing angiotensin converting enzyme (ACE) inhibitors, certain diuretics and anti-inflammatories.

Finally, the product should not be handled by pregnant women or trying to become pregnant.