Folic acid deficiency in dogs is rare but can pose a serious risk during pregnancy. This condition may affect the mother’s health and the development of her puppies. Fortunately, it can be prevented through proper nutrition and supplementation.
What causes folic acid deficiency in dogs?
While humans often develop folic acid deficiency due to poor diet, dogs rarely suffer from it for that reason. However, folate levels naturally drop during gestation. If the drop is too significant, it can become problematic. In addition, certain health conditions like gastrointestinal, pancreatic, or liver disease can reduce folate absorption and further aggravate the deficiency.
Health risks for the mother and puppies
Folic acid is essential for:
- DNA synthesis
- Red blood cell production
- Neurological and digestive system development
A deficiency can lead to:
- Anemia due to the production of immature red blood cells
- Increased risk of dystocia (difficult birth)
- Birth defects in puppies such as:
- Cleft palate
- Spinal malformations

How to prevent folic acid deficiency
Prevention starts with proper diet and care. Here’s what you can do:
- Feed a high-quality prenatal diet: Choose a formula designed for pregnant or lactating dogs
- Add folic acid supplements: Ask your vet about safe dosage and timing
- Monitor for signs of deficiency: Lethargy, poor appetite, or unusual fetal development
- Consult your vet regularly: Routine checkups help spot and prevent deficiencies early
Research shows that folic acid supplementation maintains normal blood levels and significantly lowers the risk of pregnancy complications.
Final thoughts
Folic acid deficiency in dogs during pregnancy may be rare, but its consequences can be serious. Through careful planning, proper nutrition, and veterinary guidance, you can give your pregnant dog and her puppies the best possible start. If you’re planning a pregnancy for your dog, talk to your vet about folic acid today.