What is canine brucellosis?
Brucellosis in dogs is a serious infection caused by Brucella canis. It spreads through bodily fluids like semen, urine, and vulvar discharge during heat, birthing, or miscarriage. Though primarily contagious between dogs, it presents a minor risk to humans, with over 40 human cases recorded since 1960. In the United States, it is a reportable disease.
Clinical signs of brucellosis in dogs

- In females:
- Abortion between day 45 and 55 of pregnancy
- Prolonged purulent vulvar discharge
- Stillbirth or weak puppies
- In males:
- Epididymitis and scrotal skin infections
- Testicular atrophy
- Poor-quality sperm (in chronic infections)
- In both sexes:
- Irreversible infertility
Diagnosing canine brucellosis
- AGID test (agar gel immunodiffusion): the most specific
- Three monthly serologic tests are required to confirm the diagnosis
- If all results are negative, the dog is considered uninfected
Treatment and disease control
Brucellosis is incurable, but management includes:
- Sterilization to reduce bacterial shedding (the dog remains a carrier)
- Antibiotic therapy, which cannot eliminate the infection entirely
- Hygiene precautions, especially around immunocompromised individuals
Brucellosis in breeding facilities
- Remove infected dogs from the breeding program
- Test all dogs monthly for 3 months
- Quarantine new breeding dogs for 8–12 weeks and test afterward
- Perform RSAT testing every 3–6 months
Prevention tips
- Regular brucellosis screening (RSAT)
- Spay/neuter non-breeding dogs
- Strict hygiene and isolation when needed