Brucellosis in Dogs

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What is canine brucellosis?

Brucellosis in dogs is a serious infection caused by Brucella canis. It spreads through bodily fluids like semen, urine, and vulvar discharge during heat, birthing, or miscarriage. Though primarily contagious between dogs, it presents a minor risk to humans, with over 40 human cases recorded since 1960. In the United States, it is a reportable disease.

Clinical signs of brucellosis in dogs

brucellosis in dogs
  • In females:
    • Abortion between day 45 and 55 of pregnancy
    • Prolonged purulent vulvar discharge
    • Stillbirth or weak puppies
  • In males:
    • Epididymitis and scrotal skin infections
    • Testicular atrophy
    • Poor-quality sperm (in chronic infections)
  • In both sexes:
    • Irreversible infertility

Diagnosing canine brucellosis

  • AGID test (agar gel immunodiffusion): the most specific
  • Three monthly serologic tests are required to confirm the diagnosis
  • If all results are negative, the dog is considered uninfected

Treatment and disease control

Brucellosis is incurable, but management includes:

  • Sterilization to reduce bacterial shedding (the dog remains a carrier)
  • Antibiotic therapy, which cannot eliminate the infection entirely
  • Hygiene precautions, especially around immunocompromised individuals

Brucellosis in breeding facilities

  • Remove infected dogs from the breeding program
  • Test all dogs monthly for 3 months
  • Quarantine new breeding dogs for 8–12 weeks and test afterward
  • Perform RSAT testing every 3–6 months

Prevention tips

  • Regular brucellosis screening (RSAT)
  • Spay/neuter non-breeding dogs
  • Strict hygiene and isolation when needed
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